Starting in March 2024, I have begun my new position at the University of Rochester Medical Center as an Assistant Professor, leading a lab (website) focusing on the functional genome in aging and age-related diseases.

Before joining URMC, I obtained training as a Postdoc and Research Associate in Susztak Lab in the Departments of Genetics and Medicine at the University of Pennsylvania.

Research interests

• Population Genetics
• Epigenetic Regulation
• Single Cell Omics
• Age-Related Chronic Diseases
• Developmental Origins of Diseases

News

• 03/01/2024: Liu lab (website) officially launches at the University of Rochester, with multiple Positions available. Welcome to join! :)

• 01/01/2024: We are actively seeking talented and passionate postdoctoral researchers (Computational Biology and Molecular Biology). If interested please send an email to Hongbo Liu (Hongbo_Liu@URMC.Rochester.edu) including your CV and a brief Research Statement with your background and interests.

• 08/16/2022: Our new study is published in Nature Genetics. In this study, We performed a comprehensive mapping of genetic architecture of kidney disease by integrating genomic analysis of GWAS (N=1.5 million), kidney eQTL (N=686), meQTL (N=443), snATACseq (N=60K cells), coloc, moloc, SMR, pheWAS. We proposed a multi-stage prioritization strategy and prioritized >500 kidney disease genes.
• Hongbo Liu, Tomohito Doke, Dong Guo, Xin Sheng, Ziyuan Ma, Joseph Park, Ha My T Vy, Girish N Nadkarni, Amin Abedini, Zhen Miao, Matthew Palmer, Benjamin F Voight, Hongzhe Li, Christopher D Brown, Marylyn D Ritchie, Yan Shu, Katalin Susztak✉️ (2022) Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease. Nature Genetics, 54(7):950–962.
• For more information: Paper; Research Briefing; Research Highlight; GWAS; eQTL; meQTL; snATAC-seq; Github